Twiga Study
HIV as a risk factor for geriatric syndromes, non-communicable diseases and mortality among adults aged 60 years and above in Kenya
Study Population: Adults aged 60 years and above living in Kenya, with and without HIV infection
Study Design
Prospective observational cohort study of adults ≥60 years old over a 5-year follow-up period, comparing outcomes based on HIV status. This comprehensive longitudinal study will track health outcomes, functional status, and quality of life in older adults to understand the impact of HIV on the aging process in the Kenyan population.
Primary Endpoint
Incidence of geriatric syndromes and non-communicable diseases
Frailty
Physical weakness, slowness, and decreased activity
Cognitive Decline
Memory problems and decreased mental function
Falls & Mobility
Balance problems and increased fall risk
Polypharmacy
Multiple medication use and drug interactions