Clinical Trials

Ongoing Studies & Research Programs

Our clinical trials program focuses on HIV treatment optimization, elderly care, and innovative approaches. We conduct rigorous studies to generate evidence that informs clinical practice and improves patient outcomes across Kenya and the broader region.

Active Clinical Trials

Explore our current clinical trials and research studies across multiple areas.

Recruiting

BFTAF Elderly Switch Study

Multi-centre randomized control trial assessing the efficacy and safety of switching to B/F/TAF in virologically suppressed HIV-1 positive elderly adults.

Duration:96 weeks
Participants:520 adults ≥60 years
Type:Phase 3b RCT
BFTAF Study
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Active

Twiga Study

Prospective observational cohort study examining HIV as a risk factor for geriatric syndromes and non-communicable diseases in adults ≥60 years.

Duration:5 years
Participants:Adults ≥60 years
Type:Observational Cohort
Twiga
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Active

Sungura Study

Phase 3b clinical trial assessing the efficacy and safety of switching to DTG/3TC single tablet regimen from B/F/TAF in older persons living with HIV.

Duration:96 weeks
Participants:197 participants ≥60 years
Type:Phase 3b Clinical Trial
Sungura
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Enrolling

IMPALA Study

Randomized controlled trial evaluating injectable cabotegravir/rilpivirine for improving HIV-1 control in Sub-Saharan Africa.

Duration:24 months
Participants:160 adults ≥18 years
Type:Phase 3b RCT
IMPALA
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Active

Ndovu Cohort Study

Multi-country observational study investigating optimal management of dolutegravir resistance in people with high viral load.

Duration:12 months
Participants:6,600 participants
Type:Multi-country Cohort
Ndovu Cohort
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Recruiting

Ndovu RCT

Randomized clinical trial comparing maintenance of dolutegravir versus switch to ritonavir-boosted darunavir in treatment failure.

Duration:12 months
Participants:392 participants ≥3 years
Type:Phase 3b RCT
Ndovu RCT
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